Do neuroimaging foundation models generalise to African clinical MRI?
Evaluating the Generalization of Neuroimaging Foundation Models to African Clinical MRI
Implemented the training and evaluation pipeline for BrainIAC, NeuroJEPA, NeuroVFM, and Primus on a Nigerian clinical brain-MRI cohort of 79–80 subjects, classifying Control, Dementia, and Parkinson’s disease.
Benchmarked linear probes across T1w, T2w, T1w+T2w, and FLAIR using five-fold subject-level cross-validation against an end-to-end 3D Vision Transformer.
| Approach | Finding |
|---|---|
| Four frozen backbones | Collapsed to majority-class prediction; MCC ≈ 0. |
| End-to-end ViT3D | Up to 53.4% accuracy; MCC = 0.27. Non-trivial recall across all three classes. |
These findings describe this small clinical cohort, not the models’ performance on every population or dataset.
Presentation status